It’s been around 300 years since the Salem witch trials. Those witches who remain are almost extinct and in danger once again. A school has opened in New Orleans to teach young witches how to protect themselves. The long-absent Supreme, Fiona, arrives to ensure the safety of the coven and their secrets. Fiona’s daughter, Cordelia, teaches at the school. Events reveal a long-held rivalry between the witches of Salem and the Voodoo practitioners of New Orleans, as well as an historic grudge between Voodoo Queen Marie Laveau and socialite serial killer Delphine LaLaurie.